Description
Product Characteristics:
Aliases: Organic anion transporter 4-like protein antibody, Renal-specific transporter antibody, RST antibody, S22AC_HUMAN antibody, Slc22a12 antibody, Solute carrier family 22 member 12 antibody, Urate anion exchanger 1 antibody
Target Information: The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]